Unlinked DNA under electron microscope

Since the two chains 
in our model are 
intertwined, it is 
essential for them 
to untwist if they 
are to separate.... 
although it is difficult 
at the moment 
to see how these 
processes occur 
without everything 
getting tangled... 

Watson and Crick, 1953 DNA1 DNA2
DNA3 DNA4

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