The pteridine nucleoside analog 4-amino-6-methyl-8-(2-deoxy-beta-d-ribofuranosyl)-7(8H)-pteridone (6-MAP)
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(2001) Anal. Biochem 298 231 (2001) CBB 34 257 (review) (1998) SPIE 3256 68 (1997) Anal. Biochem 244 86 (1997) Biophys J 73 3277 (1995) NAR 23 2872 CONTACT INFO 301-527-0804 (tel) 301-527-8250 (fax) fsi1@fidelitysystems.com |
The pteridine nucleoside analog 4-amino-6-methyl-8-(2-deoxy-beta-d-ribofuranosyl)-7(8H)-pteridone (6-MAP) is highly fluorescent, with a quantum yield of 0.39. Within an oligonucleotide, 6-MAP is intimately associated with native bases and its fluorescence is variably quenched in a sequence-dependent manner.
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